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CONNECT: Investigating Neural and Behavioral Characteristics of Children with Global Developmental Delays, Multisensory Deficits, and ASD Traits

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How does multisensory integration affect thinking and social development in children with global developmental delay?

This study looks at how difficulties combining information from different senses—like sound, touch, or vision—affect learning and the ability to understand others in children with global developmental delay (GDD). Using behavioral tests and brain imaging, we aim to uncover connections between these difficulties, brain activity, and autism, to guide better support for children’s development.

Research project

Sensory perception is essential for learning and social skills, but difficulties in processing sensory information can disrupt development. Children with Autism Spectrum Disorder (ASD) often experience sensory challenges that affect their ability to understand others' thoughts and feelings, known as Theory of Mind (ToM). Similar issues may occur in children with Global Developmental Delay (GDD), but this is less studied. This research explores how sensory processing difficulties in GDD impact thinking and emotions, using behavioral tests and brain scans (fMRI and DTI). By comparing GDD and typical development, the study aims to uncover shared brain patterns and improve treatments.

Research Groups

Principal Investigators: Nora Raschle, Michael von Rhein

Publications

Raschle NM, Borbás R, ...., Konrad K, Stadler C (2025)
Losing Control: Prefrontal Emotion Regulation Is Related to Symptom Severity and Predicts Treatment-Related Symptom Change in Adolescent Girls With Conduct Disorder
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 80–93

Underlined: Current and previous AdaBD researchers